NR5A1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NR5A1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NR5A1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NR5A1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NR5A1
Entrez GeneID
2516GeneBank Accession#
NR5A1Gene Name
NR5A1
Gene Alias
AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1
Gene Description
nuclear receptor subfamily 5, group A, member 1
Omim ID
184757Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq
Other Designations
OTTHUMP00000022104|OTTHUMP00000042845|OTTHUMP00000042846|OTTHUMP00000042847|adrenal 4 binding protein|fushi tarazu factor homolog 1|nuclear receptor AdBP4|steroid hormone receptor Ad4BP|steroidogenic factor 1|steroidogenic factor-1
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Interactome
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Disease
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