FTL (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human FTL full-length ORF ( AAH04245, 1 a.a. - 175 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
44.99
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FTL
Entrez GeneID
2512GeneBank Accession#
BC004245Protein Accession#
AAH04245Gene Name
FTL
Gene Alias
MGC71996
Gene Description
ferritin, light polypeptide
Gene Ontology
HyperlinkGene Summary
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq
Other Designations
L apoferritin|ferritin L subunit|ferritin L-chain|ferritin light chain|ferritin light polypeptide-like 3
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Interactome
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Disease
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Publication Reference
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Plasma hepcidin is associated with future risk of venous thromboembolism.
Ellingsen TS, Lappegård J, Ueland T, Aukrust P, Brækkan SK, Hansen JB.
Blood Advances 2018 Jun; 2(11):1191.
Application:ELISA, Human, Plasma.
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Plasma hepcidin is associated with future risk of venous thromboembolism.
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