FXN (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human FXN partial ORF (AAH48097.1, 91 a.a. - 200 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FXN
Entrez GeneID
2395GeneBank Accession#
NM_000144Protein Accession#
AAH48097.1Gene Name
FXN
Gene Alias
CyaY, FA, FARR, FRDA, MGC57199, X25
Gene Description
frataxin
Gene Ontology
HyperlinkGene Summary
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000021428
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Interactome
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Disease
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