FXN monoclonal antibody (M03), clone 3G9
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant FXN.
Immunogen
FXN (AAH48097.1, 91 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDL
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FXN expression in transfected 293T cell line by FXN monoclonal antibody (M03), clone 3G9.
Lane 1: FXN transfected lysate(23.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
RNAi Knockdown (Antibody validated)
Western blot analysis of FXN over-expressed 293 cell line, cotransfected with FXN Validated Chimera RNAi ( Cat # H00002395-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with FXN monoclonal antibody (M03), clone 3G9 (Cat # H00002395-M03 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. -
Gene Info — FXN
Entrez GeneID
2395GeneBank Accession#
NM_000144Protein Accession#
AAH48097.1Gene Name
FXN
Gene Alias
CyaY, FA, FARR, FRDA, MGC57199, X25
Gene Description
frataxin
Gene Ontology
HyperlinkGene Summary
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000021428
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Interactomes
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Diseases
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