FOLR2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human FOLR2 full-length ORF ( AAH58036.1, 1 a.a. - 255 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVWKWMPLLLLLVCVATMCSAQDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQSWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFESYFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAAMHVNAGEMLHGTGGLLLSLALMLQLWLLG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
55.7
Interspecies Antigen Sequence
Mouse (77); Rat (78)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FOLR2
Entrez GeneID
2350GeneBank Accession#
BC058036.1Protein Accession#
AAH58036.1Gene Name
FOLR2
Gene Alias
BETA-HFR, FBP/PL-1, FR-BETA, FR-P3
Gene Description
folate receptor 2 (fetal)
Omim ID
136425Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
Other Designations
folate receptor 2|folate receptor, beta|folate-binding protein, fetal/placental
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Interactome
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Disease
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