FMO5 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
FMO5 transfected lysate.
Western Blot
Lane 1: FMO5 transfected lysate ( 32.50 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FMO5 full-length
Host
Human
Theoretical MW (kDa)
32.5
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FMO5 antibody (H00002330-D01P) by Western Blots.
SDS-PAGE Gel
FMO5 transfected lysate.
Western Blot
Lane 1: FMO5 transfected lysate ( 32.50 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FMO5
Entrez GeneID
2330GeneBank Accession#
BC035687.1Protein Accession#
AAH35687.1Gene Name
FMO5
Gene Alias
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Gene Description
flavin containing monooxygenase 5
Omim ID
603957Gene Ontology
HyperlinkGene Summary
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000016306
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Interactome
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Pathway
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Disease
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