FMO4 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FMO4 full-length
Host
Human
Theoretical MW (kDa)
61.49
Interspecies Antigen Sequence
Mouse (80); Rat (81)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FMO4 antibody (H00002329-B01) by Western Blots.
SDS-PAGE Gel
FMO4 transfected lysate.
Western Blot
Lane 1: FMO4 transfected lysate ( 61.49 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FMO4
Entrez GeneID
2329GeneBank Accession#
BC002780Protein Accession#
AAH02780Gene Name
FMO4
Gene Alias
FMO2
Gene Description
flavin containing monooxygenase 4
Omim ID
136131Gene Ontology
HyperlinkGene Summary
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq
Other Designations
OTTHUMP00000033541|OTTHUMP00000060454
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