FMO2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FMO2 full-length
Host
Human
Theoretical MW (kDa)
53.6
Interspecies Antigen Sequence
Mouse (86); Rat (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FMO2 antibody (H00002327-B01) by Western Blots.
SDS-PAGE Gel
FMO2 transfected lysate.
Western Blot
Lane 1: FMO2 transfected lysate ( 53.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FMO2
Entrez GeneID
2327GeneBank Accession#
NM_001460Protein Accession#
NP_001451Gene Name
FMO2
Gene Alias
FLJ40826, FMO1B1
Gene Description
flavin containing monooxygenase 2 (non-functional)
Omim ID
603955Gene Ontology
HyperlinkGene Summary
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1. [provided by RefSeq
Other Designations
FMO, pulmonary|dimethylaniline monooxygenase [N-oxide-forming] 2|dimethylaniline oxidase 2|pulmonary flavin-containing monooxygenase 2
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Interactome
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