FKBP5 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
FKBP5 transfected lysate.
Western Blot
Lane 1: FKBP5 transfected lysate ( 51.2 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FKBP5 full-length
Host
Human
Theoretical MW (kDa)
51.2
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FKBP5 antibody (H00002289-B01) by Western Blots.
SDS-PAGE Gel
FKBP5 transfected lysate.
Western Blot
Lane 1: FKBP5 transfected lysate ( 51.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FKBP5
Entrez GeneID
2289GeneBank Accession#
NM_004117.2Protein Accession#
-Gene Name
FKBP5
Gene Alias
FKBP51, FKBP54, MGC111006, P54, PPIase, Ptg-10
Gene Description
FK506 binding protein 5
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq
Other Designations
51 kDa FK506-binding protein 5|54 kDa progesterone receptor-associated immunophilin|FF1 antigen|FK506-binding protein 5|HSP90-binding immunophilin|OTTHUMP00000016268|T-cell FK506-binding protein|peptidylprolyl cis-trans isomerase|rotamase
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Interactome
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Disease
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