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FKBP5 rabbit monoclonal antibody

  • Catalog # : H00002289-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human FKBP5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human FKBP5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human FKBP5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2289
  • GeneBank Accession#:
  • FKBP5
  • Gene Name:
  • FKBP5
  • Gene Alias:
  • FKBP51,FKBP54,MGC111006,P54,PPIase,Ptg-10
  • Gene Description:
  • FK506 binding protein 5
  • Gene Summary:
  • The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq
  • Other Designations:
  • 51 kDa FK506-binding protein 5,54 kDa progesterone receptor-associated immunophilin,FF1 antigen,FK506-binding protein 5,HSP90-binding immunophilin,OTTHUMP00000016268,T-cell FK506-binding protein,peptidylprolyl cis-trans isomerase,rotamase
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