FKBP3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
FKBP3 transfected lysate.
Western Blot
Lane 1: FKBP3 transfected lysate ( 24.75 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FKBP3 full-length
Host
Human
Theoretical MW (kDa)
24.75
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FKBP3 antibody (H00002287-B01) by Western Blots.
SDS-PAGE Gel
FKBP3 transfected lysate.
Western Blot
Lane 1: FKBP3 transfected lysate ( 24.75 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FKBP3
Entrez GeneID
2287GeneBank Accession#
NM_002013.2Protein Accession#
NP_002004.1Gene Name
FKBP3
Gene Alias
FKBP-25, PPIase
Gene Description
FK506 binding protein 3, 25kDa
Omim ID
186947Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq
Other Designations
FK506 binding protein 3 (25kD)|FK506-binding protein 25, T-cell|FK506-binding protein 3 (25kD)|peptidyl-prolyl cis-trans isomerase|rapamycin binding protein|rapamycin-selective 25 kDa immunophilin|rotamase
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Interactome
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