FKBP2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FKBP2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRTEL
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — FKBP2
Entrez GeneID
2286GeneBank Accession#
NM_004470.2Protein Accession#
NP_004461.2Gene Name
FKBP2
Gene Alias
FKBP-13, PPIase
Gene Description
FK506 binding protein 2, 13kDa
Omim ID
186946Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
FK506 binding protein 2 (13kD)|FK506-binding protein 2 (13kD)|peptidyl-prolyl cis-trans isomerase|proline isomerase|rapamycin-binding protein
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Interactome
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Disease
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