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Last updated: 2016/12/4

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FH Pre-design Chimera RNAi

  • Catalog # : H00002271-R01
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  • Specification
  • Product Description:
  • Homo sapiens fumarate hydratase (FH), nuclear gene encoding mitochondrial protein, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000143
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2271
  • Gene Name:
  • FH
  • Gene Alias:
  • HLRCC,LRCC,MCL,MCUL1
  • Gene Description:
  • fumarate hydratase
  • Gene Summary:
  • The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000037573,fumarase,multiple hereditary cutaneous leiomyomata
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