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FGR Pre-design Chimera RNAi

  • Catalog # : H00002268-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog (FGR), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005248
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2268
  • Gene Name:
  • FGR
  • Gene Alias:
  • FLJ43153,MGC75096,SRC2,c-fgr,c-src2,p55c-fgr,p58c-fgr
  • Gene Description:
  • Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • Gene Summary:
  • This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000003601,OTTHUMP00000003602,OTTHUMP00000003603,c-fgr protooncogene,c-src-2 proto-oncogene,p55-c-fgr protein,proto-oncogene tyrosine-protein kinase FGR
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