FGR (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of FGR transfected lysate using rabbit polyclonal anti-FGR and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-FGR.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84%); Rat (85%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of FGR transfected lysate using rabbit polyclonal anti-FGR and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-FGR.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-FGR (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-FGR (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — FGR
Entrez GeneID
2268Gene Name
FGR
Gene Alias
FLJ43153, MGC75096, SRC2, c-fgr, c-src2, p55c-fgr, p58c-fgr
Gene Description
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
Omim ID
164940Gene Ontology
HyperlinkGene Summary
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000003601|OTTHUMP00000003602|OTTHUMP00000003603|c-fgr protooncogene|c-src-2 proto-oncogene|p55-c-fgr protein|proto-oncogene tyrosine-protein kinase FGR
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Interactome
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Pathway
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Disease
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