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Last updated: 2017/4/23

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FGD1 Pre-design Chimera RNAi

  • Catalog # : H00002245-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) (FGD1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004463
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2245
  • Gene Name:
  • FGD1
  • Gene Alias:
  • AAS,FGDY,ZFYVE3
  • Gene Description:
  • FYVE, RhoGEF and PH domain containing 1
  • Gene Summary:
  • FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023372,faciogenital dysplasia protein
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