FGA 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FGA full-length
Host
Human
Theoretical MW (kDa)
24.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FGA antibody (H00002243-D01P) by Western Blots.
SDS-PAGE Gel
FGA transfected lysate.
Western Blot
Lane 1: FGA transfected lysate ( 24.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FGA
Entrez GeneID
2243GeneBank Accession#
BC020764Protein Accession#
AAH20764.1Gene Name
FGA
Gene Alias
Fib2, MGC119422, MGC119423, MGC119425
Gene Description
fibrinogen alpha chain
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq
Other Designations
fibrinogen, A alpha polypeptide|fibrinogen, alpha chain, isoform alpha preproprotein|fibrinogen, alpha polypeptide
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