FECH (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human FECH partial ORF ( NP_000131, 314 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FECH
Entrez GeneID
2235GeneBank Accession#
NM_000140Protein Accession#
NP_000131Gene Name
FECH
Gene Alias
EPP, FCE
Gene Description
ferrochelatase (protoporphyria)
Omim ID
177000Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ferrochelatase|heme synthetase|protoheme ferro-lyase
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Interactome
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Pathway
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Disease
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