FECH monoclonal antibody (M07), clone 3H3
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More Files
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Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FECH is 0.03 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FECH.
Immunogen
FECH (NP_000131, 314 a.a. ~ 423 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FECH is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — FECH
Entrez GeneID
2235GeneBank Accession#
NM_000140Protein Accession#
NP_000131Gene Name
FECH
Gene Alias
EPP, FCE
Gene Description
ferrochelatase (protoporphyria)
Omim ID
177000Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ferrochelatase|heme synthetase|protoheme ferro-lyase
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Interactome
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Pathway
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Disease
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