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FDPS 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00002224-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-FDPS full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 48.3
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-FDPS antibody (H00002224-D01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00002224-T02
    FDPS transfected lysate.
    Western Blot
    QC Testing of H00002224-T02
    Lane 1: FDPS transfected lysate ( 48.3 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2224
  • Gene Name:
  • FDPS
  • Gene Alias:
  • FPPS,FPS
  • Gene Description:
  • farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
  • Gene Summary:
  • This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene
  • Other Designations:
  • FPP synthetase,OTTHUMP00000015807,OTTHUMP00000015808,farnesyl diphosphate synthase
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