FDPS (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of FDPS transfected lysate using rabbit polyclonal anti-FDPS and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-FDPS.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of FDPS transfected lysate using rabbit polyclonal anti-FDPS and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-FDPS.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-FDPS (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-FDPS (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — FDPS
Entrez GeneID
2224Gene Name
FDPS
Gene Alias
FPPS, FPS
Gene Description
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
Omim ID
134629Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
FPP synthetase|OTTHUMP00000015807|OTTHUMP00000015808|farnesyl diphosphate synthase
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Interactome
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Disease
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