FCN1 monoclonal antibody (M06), clone 2B7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FCN1.
Immunogen
FCN1 (NP_001994, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESY
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FCN1 expression in transfected 293T cell line by FCN1 monoclonal antibody (M06), clone 2B7.
Lane 1: FCN1 transfected lysate(35.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FCN1 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — FCN1
Entrez GeneID
2219GeneBank Accession#
NM_002003Protein Accession#
NP_001994Gene Name
FCN1
Gene Alias
FCNM
Gene Description
ficolin (collagen/fibrinogen domain containing) 1
Omim ID
601252Gene Ontology
HyperlinkGene Summary
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq
Other Designations
OTTHUMP00000022519|ficolin (collagen/fibrinogen domain-containing) 1|ficolin 1
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Interactome
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Disease
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