FCGRT rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human FCGRT peptide using ARM Technology.
Immunogen
A synthetic peptide of human FCGRT is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human FCGRT peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — FCGRT
Entrez GeneID
2217GeneBank Accession#
FCGRTGene Name
FCGRT
Gene Alias
FCRN, alpha-chain
Gene Description
Fc fragment of IgG, receptor, transporter, alpha
Omim ID
601437Gene Ontology
HyperlinkGene Summary
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
FcRn alpha chain|IgG Gc receptor|neonatal Fc-receptor
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Interactome
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Disease
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