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FCER1A 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00002205-T02
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-FCER1A full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 29.6
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-FCER1A antibody (H00002205-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00002205-T02
    FCER1A transfected lysate.
    Western Blot
    QC Testing of H00002205-T02
    Lane 1: FCER1A transfected lysate ( 29.60 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2205
  • Gene Name:
  • FCER1A
  • Gene Alias:
  • Gene Description:
  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
  • Gene Summary:
  • The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM
  • Other Designations:
  • Fc IgE receptor, alpha polypeptide,Fc epsilon RI alpha-chain,Fc-epsilon RI-alpha,high affinity immunoglobulin epsilon receptor alpha-subunit,immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide
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