FCAR purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of FCAR expression in transfected 293T cell line (H00002204-T02) by FCAR MaxPab polyclonal antibody.
Lane 1: FCAR transfected lysate(32.30 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human FCAR protein.
Immunogen
FCAR (NP_001991.1, 1 a.a. ~ 287 a.a) full-length human protein.
Sequence
MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (53)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FCAR expression in transfected 293T cell line (H00002204-T02) by FCAR MaxPab polyclonal antibody.
Lane 1: FCAR transfected lysate(32.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — FCAR
Entrez GeneID
2204GeneBank Accession#
NM_002000.2Protein Accession#
NP_001991.1Gene Name
FCAR
Gene Alias
CD89
Gene Description
Fc fragment of IgA, receptor for
Omim ID
147045Gene Ontology
HyperlinkGene Summary
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
Fc alpha receptor|IgA Fc receptor|OTTHUMP00000068692|OTTHUMP00000068696|OTTHUMP00000068697|OTTHUMP00000068698
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Interactome
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Disease
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