EFEMP1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human EFEMP1 full-length ORF ( AAH14410, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVGQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGSENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTASSIGTFRTSSVLRLTIIVGPFSF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
79.97
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — EFEMP1
Entrez GeneID
2202GeneBank Accession#
BC014410Protein Accession#
AAH14410Gene Name
EFEMP1
Gene Alias
DHRD, DRAD, FBLN3, FBNL, FLJ35535, MGC111353, MLVT, MTLV, S1-5
Gene Description
EGF-containing fibulin-like extracellular matrix protein 1
Gene Ontology
HyperlinkGene Summary
This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. [provided by RefSeq
Other Designations
fibrillin-like|fibulin 3
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Interactome
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Disease
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Publication Reference
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EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment.
Hu Y, Pioli PD, Siegel E, Zhang Q, Nelson J, Chaturbedi A, Mathews MS, Ro DI, Alkafeef S, Hsu N, Hamamura M, Yu L, Hess KR, Tromberg BJ, Linskey ME, Zhou YH.
Molecular cancer 2001 Sep; 10(1):123.
Application:Func, Human, LN229, SNB19, U251HF cells.
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EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment.
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