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FAT Pre-design Chimera RNAi

  • Catalog # : H00002195-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens FAT tumor suppressor homolog 1 (Drosophila) (FAT), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005245
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2195
  • Gene Name:
  • FAT1
  • Gene Alias:
  • CDHF7,FAT,ME5,hFat1
  • Gene Description:
  • FAT tumor suppressor homolog 1 (Drosophila)
  • Gene Summary:
  • This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq
  • Other Designations:
  • FAT tumor suppressor 1,cadherin ME5,cadherin family member 7,cadherin-related tumor suppressor
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