FASN monoclonal antibody (M07), clone 3A2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FASN.
Immunogen
FASN (NP_004095, 2378 a.a. ~ 2477 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MEHNRVLEALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVI
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FASN is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — FASN
Entrez GeneID
2194GeneBank Accession#
NM_004104Protein Accession#
NP_004095Gene Name
FASN
Gene Alias
FAS, MGC14367, MGC15706, OA-519, SDR27X1
Gene Description
fatty acid synthase
Omim ID
600212Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq
Other Designations
short chain dehydrogenase/reductase family 27X, member 1
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Interactome
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Pathway
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Disease
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