FAP MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of FAP expression in transfected 293T cell line (H00002191-T01) by FAP MaxPab polyclonal antibody.
Lane 1: FAP transfected lysate(87.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of FAP transfected lysate using anti-FAP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with FAP purified MaxPab mouse polyclonal antibody (B01P) (H00002191-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FAP protein.
Immunogen
FAP (NP_004451.2, 1 a.a. ~ 760 a.a) full-length human protein.
Sequence
MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FAP expression in transfected 293T cell line (H00002191-T01) by FAP MaxPab polyclonal antibody.
Lane 1: FAP transfected lysate(87.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of FAP transfected lysate using anti-FAP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with FAP purified MaxPab mouse polyclonal antibody (B01P) (H00002191-B01P). -
Gene Info — FAP
Entrez GeneID
2191GeneBank Accession#
NM_004460.2Protein Accession#
NP_004451.2Gene Name
FAP
Gene Alias
DKFZp686G13158, DPPIV, FAPA
Gene Description
fibroblast activation protein, alpha
Omim ID
600403Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq
Other Designations
fibroblast activation protein, alpha subunit|integral membrane serine protease|seprase
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Interactome
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Disease
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Publication Reference
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RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α.
Xiaoliang Wang, Francois Gessier, Remo Perozzo, Darko Stojkov, Aref Hosseini, Keyvan Amirshahrokhi, Stefan Kuchen, Shida Yousefi, Pius Lötscher, Hans-Uwe Simon.
Journal of immunology 2020 Sep; 205(6):1653.
Application：IF, WB, Human, Neutrophil from PBMC.
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RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α.
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