FANCB 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FANCB full-length
Host
Human
Theoretical MW (kDa)
97.7
Interspecies Antigen Sequence
Mouse (49); Rat (50)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FANCB antibody (H00002187-B01) by Western Blots.
SDS-PAGE Gel
FANCB transfected lysate.
Western Blot
Lane 1: FANCB transfected lysate ( 97.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FANCB
Entrez GeneID
2187GeneBank Accession#
NM_001018113Protein Accession#
NP_001018123Gene Name
FANCB
Gene Alias
FA2, FAAP90, FAAP95, FAB, FACB
Gene Description
Fanconi anemia, complementation group B
Gene Ontology
HyperlinkGene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq
Other Designations
Fanconi anemia complementation group B|OTTHUMP00000022953|type 2 Fanconi pancytopenia
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