FANCA purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human FANCA protein.
Immunogen
FANCA (AAH08979, 1 a.a. ~ 297 a.a) full-length human protein.
Sequence
MSDSWVPRSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRKKLSSLLEFARYLLAHSMFSRLSFCQELWKIQSSLLLEAVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQMFVLRGFQKNSDLRRTVEPEKMPQVAVDVLQRMLIFALDALAAGVQEESSTHKIVRC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (63); Rat (72)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FANCA expression in transfected 293T cell line (H00002175-T01) by FANCA MaxPab polyclonal antibody.
Lane 1: FANCA transfected lysate(32.78 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to FANCA on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — FANCA
Entrez GeneID
2175GeneBank Accession#
BC008979Protein Accession#
AAH08979Gene Name
FANCA
Gene Alias
FA, FA-H, FA1, FAA, FACA, FAH, FANCH, MGC75158
Gene Description
Fanconi anemia, complementation group A
Gene Ontology
HyperlinkGene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq
Other Designations
Fanconi anemia, complementation group H|Fanconi anemia, type 1
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Interactome
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Disease
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