Western blot analysis of FABP3 over-expressed 293 cell line, cotransfected with FABP3 Validated Chimera RNAi ( Cat # H00002170-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with FABP3 monoclonal antibody (M01), clone 4F6-1D6 (Cat # H00002170-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq
Fatty acid-binding protein 3, muscle,OTTHUMP00000003898,fatty acid binding protein 11,fatty acid binding protein 3,mammary-derived growth inhibitor