FABP3 monoclonal antibody (M01), clone 4F6-1D6
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant FABP3.
Immunogen
FABP3 (AAH07021, 1 a.a. ~ 133 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLRTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
Host
Mouse
Reactivity
Human
Isotype
IgG2a kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (40.37 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FABP3 expression in transfected 293T cell line by FABP3 monoclonal antibody (M01), clone 4F6-1D6.
Lane 1: FABP3 transfected lysate(14.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FABP3 is approximately 0.1ng/ml as a capture antibody.ELISA
RNAi Knockdown (Antibody validated)
Western blot analysis of FABP3 over-expressed 293 cell line, cotransfected with FABP3 Validated Chimera RNAi ( Cat # H00002170-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with FABP3 monoclonal antibody (M01), clone 4F6-1D6 (Cat # H00002170-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. -
Gene Info — FABP3
Entrez GeneID
2170GeneBank Accession#
BC007021Protein Accession#
AAH07021Gene Name
FABP3
Gene Alias
FABP11, H-FABP, MDGI, O-FABP
Gene Description
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
Omim ID
134651Gene Ontology
HyperlinkGene Summary
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq
Other Designations
Fatty acid-binding protein 3, muscle|OTTHUMP00000003898|fatty acid binding protein 11|fatty acid binding protein 3|mammary-derived growth inhibitor
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Interactome
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Pathway
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Disease
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