FAAH monoclonal antibody (M07), clone 4H8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FAAH.
Immunogen
FAAH (NP_001432, 480 a.a. ~ 579 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
Host
Mouse
Reactivity
Human, Mouse, Rat
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
FAAH monoclonal antibody (M07), clone 4H8. Western Blot analysis of FAAH expression in rat brain.Western Blot (Cell lysate)
FAAH monoclonal antibody (M07), clone 4H8 Western Blot analysis of FAAH expression in A-431 ( Cat # L015V1 ).Western Blot (Cell lysate)
FAAH monoclonal antibody (M07), clone 4H8. Western Blot analysis of FAAH expression in PC-12 ( Cat # L012V1 ).Western Blot (Cell lysate)
FAAH monoclonal antibody (M07), clone 4H8. Western Blot analysis of FAAH expression in NIH/3T3(Cat # L018V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FAAH is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — FAAH
Entrez GeneID
2166GeneBank Accession#
NM_001441Protein Accession#
NP_001432Gene Name
FAAH
Gene Alias
FAAH-1, MGC102823, MGC138146
Gene Description
fatty acid amide hydrolase
Omim ID
602935Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide. [provided by RefSeq
Other Designations
OTTHUMP00000009480
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Interactome
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Disease
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Publication Reference
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N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion.
Impellizzeri D, Siracusa R, Cordaro M, Crupi R, Peritore AF, Gugliandolo E, D'Amico R, Petrosino S, Evangelista M, Di Paola R, Cuzzocrea S.
Neurobiology of Disease 2019 Jan; 125:77.
Application:WB, Mouse, Mouse hippocampus tissues.
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Dysfunction in Fatty Acid amide hydrolase is associated with depressive-like behavior in wistar kyoto rats.
Vinod KY, Xie S, Psychoyos D, Hungund BL, Cooper TB, Tejani-Butt SM.
PLoS One 2012 May; 7(5):e36743.
Application:WB-Ti, Rat, Rat brain.
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Selective alterations of the CB1 receptors and the fatty acid amide hydrolase in the ventral striatum of alcoholics and suicides.
Vinod KY, Kassir SA, Hungund BL, Cooper TB, Mann JJ, Arango V.
Journal of Psychiatric Research 2010 Jul; 44(9):591.
Application:WB, Human, Brains, Crude synaptic membrane.
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RNAi-Mediated Knockdown of Dynamin 2 Reduces Endocannabinoid Uptake Into Neuronal dCAD Cells.
McFarland MJ, Bardell TK, Yates ML, Placzek EA, Barker E.
Molecular Pharmacology 2008 Apr; 74(1):101.
Application:WB-Tr, Mouse, CAD cells.
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N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion.
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