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F11 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00002160-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-F11 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 70.1
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-F11 antibody (H00002160-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00002160-T01
    F11 transfected lysate.
    Western Blot
    QC Testing of H00002160-T01
    Lane 1: F11 transfected lysate ( 70.1 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2160
  • Protein Accession#:
  • -
  • Gene Name:
  • F11
  • Gene Alias:
  • FXI,MGC141891
  • Gene Description:
  • coagulation factor XI
  • Gene Summary:
  • This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq
  • Other Designations:
  • plasma thromboplastin antecedent,platelet coagulation factor XI
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