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F3 Pre-design Chimera RNAi

  • Catalog # : H00002152-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens coagulation factor III (thromboplastin, tissue factor) (F3), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001993
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2152
  • Gene Name:
  • F3
  • Gene Alias:
  • CD142,TF,TFA
  • Gene Description:
  • coagulation factor III (thromboplastin, tissue factor)
  • Gene Summary:
  • This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000012426,coagulation factor III,tissue factor
  • Interactome
  • Interactome
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