F3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and F3 expressing 293 cells (Green) using F3 purified MaxPab mouse polyclonal antibody.
Western Blot (Tissue lysate)
F3 MaxPab polyclonal antibody. Western Blot analysis of F3 expression in human pancreas.
Western Blot (Cell lysate)
F3 MaxPab polyclonal antibody. Western Blot analysis of F3 expression in A-431.
Western Blot (Transfected lysate)
Western Blot analysis of F3 expression in transfected 293T cell line (H00002152-T01) by F3 MaxPab polyclonal antibody.
Lane 1: F3 transfected lysate(32.45 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human F3 protein.
Immunogen
F3 (AAH11029.1, 1 a.a. ~ 295 a.a) full-length human protein.
Sequence
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (55); Rat (55)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and F3 expressing 293 cells (Green) using F3 purified MaxPab mouse polyclonal antibody.Western Blot (Tissue lysate)
F3 MaxPab polyclonal antibody. Western Blot analysis of F3 expression in human pancreas.Western Blot (Cell lysate)
F3 MaxPab polyclonal antibody. Western Blot analysis of F3 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of F3 expression in transfected 293T cell line (H00002152-T01) by F3 MaxPab polyclonal antibody.
Lane 1: F3 transfected lysate(32.45 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — F3
Entrez GeneID
2152GeneBank Accession#
NM_001993Protein Accession#
AAH11029.1Gene Name
F3
Gene Alias
CD142, TF, TFA
Gene Description
coagulation factor III (thromboplastin, tissue factor)
Omim ID
134390Gene Ontology
HyperlinkGene Summary
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [provided by RefSeq
Other Designations
OTTHUMP00000012426|coagulation factor III|tissue factor
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Interactome
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Pathway
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Disease
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Publication Reference
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A Unique Protein Kinase C-Dependent Pathway for Tissue Factor Downregulation in Pericytes.
Sommerville LJ, Gorman KL, Snyder SA, Monroe DM, Hoffman M.
Journal of Thrombosis and Haemostasis 2019 Apr; 17(4):670.
Application：IF, WB, Human, Pericytes.
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A Unique Protein Kinase C-Dependent Pathway for Tissue Factor Downregulation in Pericytes.
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