F2RL1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human F2RL1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — F2RL1
Entrez GeneID
2150GeneBank Accession#
BC012453.1Protein Accession#
AAH12453.1Gene Name
F2RL1
Gene Alias
GPR11, PAR2
Gene Description
coagulation factor II (thrombin) receptor-like 1
Omim ID
600933Gene Ontology
HyperlinkGene Summary
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq
Other Designations
G protein-coupled receptor-11|protease-activated receptor 2|proteinase-activated receptor-2
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Interactome
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Disease
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