F2RL1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human F2RL1 partial ORF ( AAH18130, 38 a.a. - 149 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.95
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — F2RL1
Entrez GeneID
2150GeneBank Accession#
BC018130Protein Accession#
AAH18130Gene Name
F2RL1
Gene Alias
GPR11, PAR2
Gene Description
coagulation factor II (thrombin) receptor-like 1
Omim ID
600933Gene Ontology
HyperlinkGene Summary
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq
Other Designations
G protein-coupled receptor-11|protease-activated receptor 2|proteinase-activated receptor-2
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Interactome
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Disease
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