F2 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of F2 expression in transfected 293T cell line (H00002147-T01) by F2 MaxPab polyclonal antibody.
Lane 1: F2 transfected lysate(70.00 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of F2 transfected lysate using anti-F2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with F2 purified MaxPab mouse polyclonal antibody (B01P) (H00002147-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human F2 protein.
Immunogen
F2 (NP_000497.1, 1 a.a. ~ 622 a.a) full-length human protein.
Sequence
MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of F2 expression in transfected 293T cell line (H00002147-T01) by F2 MaxPab polyclonal antibody.
Lane 1: F2 transfected lysate(70.00 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of F2 transfected lysate using anti-F2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with F2 purified MaxPab mouse polyclonal antibody (B01P) (H00002147-B01P). -
Gene Info — F2
Entrez GeneID
2147GeneBank Accession#
NM_000506Protein Accession#
NP_000497.1Gene Name
F2
Gene Alias
PT
Gene Description
coagulation factor II (thrombin)
Omim ID
176930Gene Ontology
HyperlinkGene Summary
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq
Other Designations
coagulation factor II|prothrombin B-chain|serine protease
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Interactome
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Pathway
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Disease
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