EXT2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human EXT2 partial ORF ( AAH10058, 216 a.a. - 315 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — EXT2
Entrez GeneID
2132GeneBank Accession#
BC010058Protein Accession#
AAH10058Gene Name
EXT2
Gene Alias
SOTV
Gene Description
exostoses (multiple) 2
Gene Ontology
HyperlinkGene Summary
This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase|N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase|exostosin 2
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Interactome
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Pathway
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Disease
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