EXT2 monoclonal antibody (M01), clone 3G6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant EXT2.
Immunogen
EXT2 (AAH10058, 216 a.a. ~ 315 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEA
Host
Mouse
Reactivity
Human
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
EXT2 monoclonal antibody (M01), clone 3G6. Western Blot analysis of EXT2 expression in human spleen.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EXT2 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — EXT2
Entrez GeneID
2132GeneBank Accession#
BC010058Protein Accession#
AAH10058Gene Name
EXT2
Gene Alias
SOTV
Gene Description
exostoses (multiple) 2
Gene Ontology
HyperlinkGene Summary
This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase|N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase|exostosin 2
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Interactome
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Pathway
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Disease
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