ETFDH (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ETFDH partial ORF ( NP_004444.1, 518 a.a. - 617 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LLSSVALSGTNHEHDQPAHLTLRDDSIPVNRNLSIYDGPEQRFCPAGVYEFVPVEQGDGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ETFDH
Entrez GeneID
2110GeneBank Accession#
NM_004453Protein Accession#
NP_004444.1Gene Name
ETFDH
Gene Alias
ETFQO, MADD
Gene Description
electron-transferring-flavoprotein dehydrogenase
Gene Ontology
HyperlinkGene Summary
Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia. [provided by RefSeq
Other Designations
ETF-ubiquinone oxidoreductase|Electron transfer flavoprotein:ubiquinone oxidoreductase|electron transfer flavoprotein ubiquinone oxidoreductase
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Interactome
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Disease
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