ESRRA (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ESRRA partial ORF ( NP_004442, 231 a.a. - 330 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ESRRA
Entrez GeneID
2101GeneBank Accession#
NM_004451Protein Accession#
NP_004442Gene Name
ESRRA
Gene Alias
ERR1, ERRa, ERRalpha, ESRL1, NR3B1
Gene Description
estrogen-related receptor alpha
Omim ID
601998Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq
Other Designations
estrogen receptor-like 1
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Interactome
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Disease
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