ESR2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ESR2 full-length
Host
Human
Theoretical MW (kDa)
35.9
Interspecies Antigen Sequence
Mouse (87)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ESR2 antibody (H00002100-D01P) by Western Blots.
SDS-PAGE Gel
ESR2 transfected lysate.
Western Blot
Lane 1: ESR2 transfected lysate ( 35.90 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ESR2
Entrez GeneID
2100GeneBank Accession#
BC024181.2Protein Accession#
AAH24181.1Gene Name
ESR2
Gene Alias
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Gene Description
estrogen receptor 2 (ER beta)
Omim ID
601663Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq
Other Designations
estrogen receptor beta|estrogen receptor beta 4
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Interactome
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Disease
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