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ERN1 rabbit monoclonal antibody

  • Catalog # : H00002081-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ERN1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ERN1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ERN1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2081
  • GeneBank Accession#:
  • ERN1
  • Gene Name:
  • ERN1
  • Gene Alias:
  • FLJ30999,IRE1,IRE1P,MGC163277,MGC163279
  • Gene Description:
  • endoplasmic reticulum to nucleus signaling 1
  • Gene Summary:
  • The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq
  • Other Designations:
  • ER to nucleus signalling 1,endoplasmic reticulum to nucleus signalling 1,inositol-requiring 1,protein kinase/endoribonuclease
  • Interactome
  • Interactome
  • Gene Pathway
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