ERN1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ERN1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ERN1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ERN1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ERN1
Entrez GeneID
2081GeneBank Accession#
ERN1Gene Name
ERN1
Gene Alias
FLJ30999, IRE1, IRE1P, MGC163277, MGC163279
Gene Description
endoplasmic reticulum to nucleus signaling 1
Omim ID
604033Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq
Other Designations
ER to nucleus signalling 1|endoplasmic reticulum to nucleus signalling 1|inositol-requiring 1|protein kinase/endoribonuclease
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