ERCC6 polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant ERCC6.
Immunogen
ERCC6 (NP_000115, 1394 a.a. ~ 1493 a.a) partial recombinant protein with GST tag.
Sequence
RARNHLILPERLESESGHLQEASALLPTTEHDDLLVEMRNFIAFQAHTDGQASTREILQEFESKLSASQSCVFRELLRNLCTFHRTSGGEGIWKLKPEYC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (76)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ERCC6
Entrez GeneID
2074GeneBank Accession#
NM_000124Protein Accession#
NP_000115Gene Name
ERCC6
Gene Alias
ARMD5, CKN2, COFS, COFS1, CSB, RAD26
Gene Description
excision repair cross-complementing rodent repair deficiency, complementation group 6
Gene Ontology
HyperlinkGene Summary
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B. [provided by RefSeq
Other Designations
Cockayne syndrome group B protein|OTTHUMP00000019581|Rad26 homolog
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Interactomes
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Pathways
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Diseases
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