ERCC5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ERCC5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ERCC5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ERCC5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ERCC5
Entrez GeneID
2073GeneBank Accession#
ERCC5Gene Name
ERCC5
Gene Alias
COFS3, ERCM2, UVDR, XPG, XPGC
Gene Description
excision repair cross-complementing rodent repair deficiency, complementation group 5
Gene Ontology
HyperlinkGene Summary
Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000064902|XPG-complementing protein|excision repair protein|xeroderma pigmentosum complementation group G protein|xeroderma pigmentosum, complementation group G
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