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ERCC5 rabbit monoclonal antibody

  • Catalog # : H00002073-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ERCC5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ERCC5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ERCC5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2073
  • GeneBank Accession#:
  • ERCC5
  • Gene Name:
  • ERCC5
  • Gene Alias:
  • COFS3,ERCM2,UVDR,XPG,XPGC
  • Gene Description:
  • excision repair cross-complementing rodent repair deficiency, complementation group 5
  • Gene Summary:
  • Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000064902,XPG-complementing protein,excision repair protein,xeroderma pigmentosum complementation group G protein,xeroderma pigmentosum, complementation group G
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