ERCC3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ERCC3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ERCC3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ERCC3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ERCC3
Entrez GeneID
2071GeneBank Accession#
ERCC3Gene Name
ERCC3
Gene Alias
BTF2, GTF2H, RAD25, TFIIH, XPB
Gene Description
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
Gene Ontology
HyperlinkGene Summary
ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription. [provided by RefSeq
Other Designations
OTTHUMP00000162265|excision repair cross-complementing rodent repair deficiency, complementation group 3|xeroderma pigmentosum, complementation group B
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