EPOR 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
Western Blot
Lane 1: EPOR transfected lysate ( 55.1 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
EPOR transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-EPOR full-length
Host
Human
Theoretical MW (kDa)
55.99
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-EPOR antibody (H00002057-B01) by Western Blots.
Western Blot
Lane 1: EPOR transfected lysate ( 55.1 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
EPOR transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — EPOR
Entrez GeneID
2057GeneBank Accession#
NM_000121Protein Accession#
NP_000112Gene Name
EPOR
Gene Alias
MGC138358
Gene Description
erythropoietin receptor
Gene Ontology
HyperlinkGene Summary
The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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